KEGG   Homo sapiens (human): 10724
Entry
10724             CDS       T01001                                 
Symbol
OGA, MEA5, MGEA5, NCOAT
Name
(RefSeq) O-GlcNAcase
  KO
K15719  protein O-GlcNAcase / histone acetyltransferase [EC:3.2.1.169 2.3.1.48]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04931  Insulin resistance
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    10724 (OGA)
Enzymes [BR:hsa01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.48  histone acetyltransferase
     10724 (OGA)
 3. Hydrolases
  3.2  Glycosylases
   3.2.1  Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
    3.2.1.169  protein O-GlcNAcase
     10724 (OGA)
SSDB
Motif
Pfam: NAGidase
Other DBs
NCBI-GeneID: 10724
NCBI-ProteinID: NP_036347
OMIM: 604039
HGNC: 7056
Ensembl: ENSG00000198408
UniProt: O60502
Structure
Position
10:complement(101784450..101818444)
AA seq 916 aa
MVQKESQATLEERESELSSNPAASAGASLEPPAAPAPGEDNPAGAGGAAVAGAAGGARRF
LCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWREMYSVEEAEQLM
TLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNM
CAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEK
LLPGIEVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRS
TELIPRLKGVLTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSEDSTVSIQIKLE
NEGSDEDIETDVLYSPQMALKLALTEWLQEFGVPHQYSSRQVAHSGAKASVVDGTPLVAA
PSLNATTVVTTVYQEPIMSQGAALSGEPTTLTKEEEKKQPDEEPMDMVVEKQEETDHKND
NQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIAPMQTDEQTNKEQFVP
GPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVSVNCKGKD
SEKIEEWRSRAAKFEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQW
LGCRSHSSAQFLIGDQEPWAFRGGLAGEFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPY
FPKDEASVYKICREMYDDGVGLPFQSQPDLIGDKLVGGLLSLSLDYCFVLEDEDGICGYA
LGTVDVTPFIKKCKISWIPFMQEKYTKPNGDKELSEAEKIMLSFHEEQEVLPETFLANFP
SLIKMDIHKKVTDPSVAKSMMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIA
KMEGFPKDVVILGRSL
NT seq 2751 nt   +upstreamnt  +downstreamnt
atggtgcagaaggagagtcaagcgacgttggaggagcgggagagcgagctcagctccaac
cctgccgcctctgcgggggcatcgctggagccgccggcagctccggcacccggagaagac
aaccccgccggggctgggggagcggcggtggccggggctgcaggaggggctcggcggttc
ctctgcggtgtggtggaaggattttatggaagaccttgggttatggaacagagaaaagaa
ctctttagaaggctccagaaatgggaattaaatacatacttgtatgccccaaaagatgac
tacaaacataggatgttttggcgagagatgtattcagtggaggaagctgagcaacttatg
actctcatctctgctgcacgagaatatgagatagagttcatctatgcgatctcacctgga
ttggatatcactttttctaaccccaaggaagtatccacattgaaacgtaaattggaccag
gtttctcagtttgggtgcagatcatttgctttgctttttgatgatatagaccataatatg
tgtgcagcagacaaagaggtattcagttcttttgctcatgcccaagtctccatcacaaat
gaaatctatcagtacctaggagagccagaaactttcctcttctgtcccacagaatactgt
ggcactttctgttatccaaatgtgtctcagtctccatatttaaggactgtgggtgaaaag
cttctacctggaattgaagtgctttggacaggtcccaaagttgtttctaaagaaattcca
gtagagtccatcgaagaggtttctaagattattaagagagctccagtaatctgggataac
attcatgctaatgattatgatcagaagagactgtttctgggcccgtacaaaggaagatcc
acagaactcatcccacggttaaaaggagtcctcactaatccaaattgtgaatttgaagcc
aactacgttgctatccacacccttgccacctggtacaaatcaaacatgaatggagtgaga
aaagatgtagtgatgactgacagtgaagatagtactgtgtccatccagataaaattagaa
aatgaaggcagtgatgaagatattgaaactgatgtactctatagtccacagatggctcta
aagctagcattaacagaatggttgcaagagtttggtgtgcctcatcaatacagcagtagg
caagttgcacacagtggagctaaagcaagtgtagttgatgggactcctttagttgcagca
ccctctttaaatgccacaaccgtagtaacaacagtttatcaggagcccattatgagccag
ggagcagccttgagtggtgagcctactactctgaccaaggaagaagaaaagaaacagcct
gatgaagaacccatggacatggtggtggaaaaacaagaagaaacggaccacaagaatgac
aatcaaatactgagtgaaattgttgaagcgaaaatggcagaggaattgaaaccaatggac
actgataaagagagcatagctgaatcaaaatccccagagatgtccatgcaagaagattgt
attagtgacattgcccccatgcaaactgatgaacagacaaacaaggagcagtttgtgcca
ggtccaaatgaaaagcctttgtacactgcggaaccagtgaccctggaggatttgcagtta
cttgctgatctattctaccttccttacgagcatggacccaaaggagcacagatgttacgg
gaatttcaatggcttcgagcaaatagtagtgttgtcagtgtcaattgcaaaggaaaagac
tctgaaaaaattgaagaatggcggtcacgagcagccaagtttgaagagatgtgtggacta
gtgatgggaatgttcactcggctctccaattgtgccaacaggacaattctttatgacatg
tactcctatgtttgggatatcaagagtataatgtctatggtgaagtcttttgtacagtgg
ttagggtgtcgtagtcattcttcagcacaattcttaattggagaccaagaaccctgggcc
tttagaggtggtctagcaggagagttccagcgtttgctgccaattgatggggcaaatgat
ctcttttttcagccacctccactgactcctacctccaaagtttatactatcagaccttat
tttcctaaggatgaggcatccgtgtacaagatttgcagagaaatgtatgacgatggagtg
ggtttaccctttcaaagtcagcctgatcttattggagacaagttagtaggagggctgctt
tccctcagcctggattactgctttgtcctagaagatgaagatggcatatgtggttatgcc
ttgggcactgtagatgtgaccccctttattaaaaaatgtaaaatttcctggatccccttc
atgcaggagaagtataccaagccaaatggtgacaaggaactctctgaggctgagaaaata
atgttgagtttccatgaagaacaggaagtactgccagaaactttccttgctaatttccct
tctctgataaagatggacattcacaaaaaagtaactgacccaagtgtggccaaaagcatg
atggcttgcctcctgtcttcactgaaggctaatggctcccggggagctttctgtgaagtg
agaccagatgataaaagaattctggaattttacagcaagttaggatgttttgaaattgca
aaaatggaaggatttccaaaggatgtggttatacttggtcggagcctgtga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (4)   
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   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (23)   
   KEGG ORTHOLOGY (1)   
   RefGene (11)   
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   RIKEN BRC-DNA (6)   
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Protein sequence (14)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (12)   
DNA sequence (42)   
   RefSeq(nuc) (14)   
   GenBank (14)   
   EMBL (14)   
3D Structure (22)   
   PDB (22)   
Protein domain (1)   
   Pfam (1)   
All databases (117)   

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